pentobarbital will reduce the level or impact of theophylline by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep an eye on.
pentobarbital will decrease the level or impact of aripiprazole by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Watch.
pentobarbital will lower the extent or outcome of buprenorphine, very long-performing injection by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Keep track of Carefully. Individuals who transfer to buprenorphine prolonged-acting injection from transmucosal buprenorphine coadministered with CYP3A4 inducers must be monitored to be sure buprenorphine plasma degrees are suitable.
C: Use with caution if Positive aspects outweigh pitfalls. Animal reports present threat and human research not accessible or neither animal nor human studies carried out.
pentobarbital will lessen the extent or outcome of losartan by impacting hepatic enzyme CYP2C9/10 metabolism. Minor/Importance Not known.
Pentobarbital administration is thru IM, IV, or oral routes. For IM administration, injecting no more than five mL and only into a considerable muscle in order to avoid tissue discomfort or necrosis is suggested.
pentobarbital will lessen the extent or outcome of quinidine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Observe.
pentobarbital will minimize the extent or outcome of lorlatinib by influencing hepatic/intestinal enzyme CYP3A4 metabolism.
pentobarbital will reduce the level or result of verapamil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Monitor.
pentobarbital decreases levels of amphotericin B deoxycholate by inhibition of GI absorption. Applies only to oral type of each agents. Insignificant/Significance Unknown.
Untimely infants are notably prone to the depressant effects of barbiturates; if barbiturates are used all through labor and shipping, resuscitation tools should be readily available
Warning when discontinuing CYP3A4 inducers which have been coadministered with benzhydrocodone (prodrug of hydrocodone); plasma concentrations of hydrocodone may well enhance and may end up in probably fatal respiratory check here depression.
pentobarbital will reduce the level or effect of darunavir by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep an eye on.
pentobarbital will reduce the extent or result of itraconazole by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Minimal/Significance Mysterious.